Oct 272011
How Do We Know That Herd Immunity Exists?

The term “herd immunity” elicits strong responses from some in the anti-vaccine camp. Perhaps some do not like the use of the word “herd” because of its association with sheep, or other such animals that do the bidding of their herders. Or perhaps, and this is my belief, it is because the very idea of herd immunity rests upon the premise that vaccines are effective at stopping disease progression, and vaccine efficacy is one of the major things anti-vaxers deny. Many times they demand proof that herd immunity exists. In and of itself, that request is not unreasonable. After all, scientific proof ———->FULL ARTICLE

Flash News – 01/28/11

 Posted by on January 28, 2011  1 Response »
Jan 282011

Studies show rotavirus vaccine very effective in reducing rotavirus related, and all-cause, diarrhea hospitalizations rates – Twelve studies published as a special supplement in The Pediatric Infectious Disease Journal show sustained declines in hospitalizations due to rotavirus in children under 5 in countries that include rotavirus vaccines as part of their routine immunization programs. More specifically they show the following: El Salvador – rotavirus hospitalization rates years declined by 81%  in 2008 when two-dose rotavirus vaccine coverage was 50% among newborns. The decline was about 69% in 2009 when the two-dose vaccine coverage grew to 61% among newborns Mexico – there ———->FULL ARTICLE

Jan 212011

A recent study, published in the journal Pediatrics in December 2010, provides further evidence that the pentavalent rotavirus vaccine is effective in reducing hospitalization and emergency visits attributable to rotavirus gastroenteritis, without increased risk of intussusception or other serious adverse events, among infants aged 6-12 weeks of age. Pentavalent Rotavirus Vaccine in Developing Countries: Safety and Health Care Resource Utilization Celia D. C. Christie, MBBS, DMPeds, MPH, FAAP, FRCPa, Newton D. Duncan, MBBS, DMSurg, FACSb, Kirk A. Thame, MBBS, DMPeds, FAAPa, Matthew T. Onorato, BScc, Hyacinth D. Smith, RN, RM, MPHa, Lavern G. Malcolm, BSc, RN, MPHa, Robbin F. Itzler, ———->FULL ARTICLE

Oct 022010

I have previously looked at studies that looked at acute gastroenteritis (AGE) rates of hospitalizations before and after the introduction of the pentavalent rotavirus vaccine (RV5). Those studies noted a significant reduction in AGE hospitalization rates following the introduction of the RV5 in 2006. In this entry, I will summarize yet another study along the same lines. AGE, commonly referred to as the “stomach flu“,  is a viral infection, and rotavirus is the leading cause of severe gastroenteritis in children, credited with causing about 50% of acute gastroenteritis hospitalizations during January-June among U.S. children. Logically, if rotavirus causes it, and if ———->FULL ARTICLE

Aug 102010

Two new studies, published online in The Lancet (the full text can be accessed here and here; free registration to The Lancet required), have produced similar results to the results of a similar US study on which I reported here at Vaccine Central which showed the RotaTeq pentavalent rotavirus vaccine to be 45% in reducing all cause gastroenteritis hospitalization rates, an excellent track record given that the rotavirus is credited with causing up to 50% of all cause gastroenteritis hospitalizations in children. At that time, I concluded that although the study showed a strong correlation between the introduction of the ———->FULL ARTICLE

May 132010

A new analysis, published online by The Journal of Infectious Diseases, takes a look at acute gastroenteritis hospitalization (AGE) rates among US children under 5 years old, before and after the introduction of the first Rotavirus vaccine, RotaTeq (RV5) in early 2006. The objective of this analysis was to see if there was any change in gastroenteritis hospitalization rates after the vaccine was licensed for use among infants in the United States. The study I am referring to is this one: Reduction in Acute Gastroenteritis Hospitalizations among US Children After Introduction of Rotavirus Vaccine: Analysis of Hospital Discharge Data from ———->FULL ARTICLE